Background TB and HIV remain the major health problem in Uganda. HIV is the leading risk after for the development of TB and TB is the leading cause of death in people with HIV/AIDS with the prevalenceof7.3% and approximated 50-60%of TB patients co-infected with HIV. The purpose of this study was to compile a report on the prevalence of pulmonary TB in HIV sero-positive patients attending ART clinic at Entebbe grade B hospital. . Methods: across sectional study was used for all males and female of any age attending Entebbe grade B hospital. Results among the 200 HIV sero-positive patients interviewed, 14% were co-infected with TB and among them,64% were males and 36% were females. Patients having a low CD4 below 250 were highly pre disposed to TB with 23% followed by smoking with16%.Patients with drenching night sweats had the highest percentage of smear positive with43% followed by cough with 28%. Conclusion since the increase in HIV infection rate leads to increase in TB disease, there is need to re-examine the strategies for their control, the development of programs with an integrated approach to inducing behavioral change and promoting condom use may reduce the infectivity of HIV transmitters and the susceptibility of HIV exposed persons. Recommendation all patients attending HIV clinic should be assessed and tested for TB .HIV and TB mass awareness campaigns among people. This should be done at community level as part of primary health care.

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