The objective of the study was to establish the factors that are associated with completion of recommended Post-Exposure Prophylaxis (PEP) regimen in Uganda in the districts neighbouring Queen Elizabeth National Park. The assessment was made by socio- demographic and economic factors, dog bites and PEP vaccination and rabies vaccination strategies used to reduce rabies after animal bites. Primary data was compiled from a sample of 130 respondents using a structured questionnaire. The analysis was done using frequency distribution, Chi-square statistics and binary logistic regression. The results showed that 91.5% of the victims had completed rabies Post-Exposure Prophylaxis. In particular, completion of recommended Post-Exposure Prophylaxis regimen was more likely among households that were far away from the national park (OR=6.88; p-value=0.018), members that were bitten in the rainy season (OR=5.59; p-value=0.034) and those who sought treatment from the hospital (OR=2.24; p-value=0.029). On the contrary, completion of recommended Post-Exposure Prophylaxis regimen was less likely among households whose heads were in the age group of 51 to 60 years (OR=0.019; p-value=0.017). The factors associated with completion of recommended PEP regimen in the districts neighbouring Queen Elizabeth National Park are proximity to the national park, age of the household head, season of the dog bite and category of the health centre. Thus, bitten victims should receive counselling with documented medical providers’ recommendations and should be closely followed to ensure the compliance of PEP, by using either follow-up calls or short message service text messages.

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