Background: Immunization is generally considered the most successful and cost-effective public health intervention employed today (CDC, 2011). The widespread use of vaccines for immunization, has resulted in the global eradication of smallpox, elimination of polio and measles from many countries. Coverage with the third dose of diphtheria-pertussis-tetanus vaccine (DPT3) is a widely used indicator of the performance of countries’ routine immunization services. In Uganda WHO /UNICEF, 2014 estimated that immunization coverage at on DPT 3 was only 52%. DPT vaccine is given by injection on the left upper thigh at 6 weeks, 10 weeks and 14 weeks. Various approaches have been applied to understand immunization coverage problems. Objective: The purpose of study was to determine factors associated with uptake of DPT 3 Immunization amongst children aged 6-12 months in-order to contribute partly in the improvement of DPT3 immunization Methods: This research essentially took on a descriptive cross sectional survey design. In this study the target population was study caretakers of children aged 6-12 months, 384 caretakers of children aged 6-12 months in selected households in households Kawempe-Mbogo village, Kawempe division, Kampala District. Respondents were recruited using the probability simple random after mapping it gives all the household equal chance to participate. The researcher chose to use, structured interviews to collect the required data from the study respondents. The structured questionnaire was used to collect data from respondents and data was analyzed using SPSS version 20. Results: From the data analyzed, the level of completion of was moderate at 56.2%. Place of delivery, monthly income and payment for immunization services were significantly associated with DPT3 completion among the respondents children Conclusions and Recommendations: In conclusion, this study revealed that the DPT3 immunization completion was moderate. Therefore the study recommends increased awareness concerning delivery at health facilities should also be created among the community as this is associated with higher likelihood of childhood immunization and health facility that provide EPI services should strengthening of continuous staff motivation, regular supervision.

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