Background: HIV sero-status disclosure is a crucial canvas upon which ART adherence and prevention of transmission can be built. This study sought to assess factors associated with disclosure of HIV sero-status among women attending ART clinic follow up between the months of November to May 2018 at Nabweru Health Center III, Wakiso District. Methods: the study was a cross-sectional design carried out among women attending ART clinic at Nabweru Health Center III, Wakiso district. 100 participants were invited to participate in the study; these were selected using simple random sampling. SPSS Version 24 was used to analyze the finding while as p<0.05 was considered significant in this study. Results: 100 participants completed the survey. The prevalence of disclosure was 76%. Independent predictors of disclosure included: awareness of partners’ sero-status, fear of disclosure, reasons for fear of disclosure and post-test counseling. Conclusion: The disclosure rate reported in this study is significant. This study provided potential evidence on factors associated with disclosure which could support implementation of effective community health interventions attempting HIV identity transformation to foster disclosure which has been shown to have seminal benefits to an individual and the community. This evidence could also be useful for individuals, cultures and environment where disclosure of HIV sero-status is impended by fear, stigma and health facility limitations. Disclosure should be the pinnacle of Pre and Post-counseling and should be considered a seminal concern of healthcare providers of various disciplines who care for persons living with HIV as well as health authorities, municipalities and community organizations.

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